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Pertuzumab and Vismodegib Added to Proposition 65 (February 2017)

Effective January 27, 2017, the Office of Environmental Health Hazard Assessment (OEHHA) added Pertuzumab and Vismodegib to the Proposition 65 list of chemicals known to the state to cause developmental and/or reproductive toxicity. Pertuzumab and Vismodegib are both drugs used to treat certain types of cancer.

Chemical CAS No. Endpoints Listing Mechanism
Pertuzumab 380610-27-5 Developmental Toxicity FR
Vismodegib 879085-55-9 Developmental Toxicity
Female Reproductive Toxicity
Male Reproductive Toxicity
FR

FR Listing

A chemical is listed under the FR mechanism when a state or federal agency requires it to be labeled or identified as causing cancer or toxicity. The Food and Drug Administration (FDA) has identified Pertuzumab and Vismodegib as chemicals that cause reproductive and developmental harm.

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